Contents page 1 — HIV-cure, the second page 2 — “The first successful repeat of the Berlin patient,” On a page
read 37 million Infected worldwide, one Million Deaths every year – and now a second person who may have been cured. In his body, the HI is not detect Virus even in the smallest fragments. What a blessing it would be if the disease that causes Aids, would be for all of a cure?
In the current case, it succeeded in Doctors from London, to remove the Virus from the body of a man. Over a period of almost three years after a stem cell transplant, which he received due to advanced cancer, could be detected in the blood of patients in the absence of virus particles. This should remain so, would this man, we call him the London patients, only the second, would have helped in such a targeted treatment. Cured means that without medication, the Virus is no longer detected in the body.
The case, the the the researchers in the journal Nature (Gupta et al., 2019) describe, strongly reminiscent of the story of Timothy Ray Brown. He was freed more than ten years ago in the Charité hospital in Berlin-Steglitz of HIV and became known as the Berlin Patient in the story (the New England Journal of Medicine: Hütter et al., 2009).
Not only the treatment of the two was similar, as well in particular circumstances. For this reason alone, their treatments for almost none of the millions of HIV patients, and no patients in the world out of the question.
A rare Mutation as a stroke of luck
Already in 2003, the London Patient was diagnosed with HIV in December of 2012, he was diagnosed with lymphatic cancer, Hodgkin’s lymphoma. The Doctors gave him different chemo therapies that didn’t work right. The only thing that promised to help: a bone marrow transplant, the patient’s immune system should be replaced. Thus, the cancer cells in the patients were originated from immune cells, should disappear. Because a transplant with their own stem cells – the Option, the Medicine they prefer and the practitioners because of fewer side effects was not possible, were looking for the Doctors in a bone marrow register for a donor or a donor.
HIV and Aids What are HIV and Aids?
The human immunodeficiency virus (HIV) is a so-called Retrovirus. It writes its genetic material into the genome of the host cell and forces them to reproduce it. HIV infects different body cells, including important cells of the immune system such as phagocytes (macrophages), and helper T cells that coordinate the immune response. In the result, the T-helper cells either die because of cracks in their cell wall, if you make new virus particles into the bloodstream, they initiate programmed cell death, or be killed by their own immune system, because of this you will recognize as infected.
the infection Is not treated, it decreases the number of T-helper cells, the immune system is weaker. The final stage of immunodeficiency is Aids (acquired immunodeficiency syndrome). Aids is inflammation due to life-threatening infections such as lung with aggressive fungi, inflammation of the brain, but also through cancer characterized diseases.
